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Understanding Your Lab Values and CKD Health Numbers

  • Living with chronic kidney disease (CKD) can feel like learning a new language due to its complexity and progression. Initially, only a few tests might be necessary, but as CKD worsens, your kidneys struggle more with their functions, requiring more frequent and varied testing. This includes monitoring for related health conditions.
  • Regular visits with healthcare professionals and completing recommended lab work are crucial for staying informed about your health. This guide provides a quick overview of the key health indicators you may find in your medical records, particularly important for CKD patients. These tests may involve blood or urine samples sent to a lab or measurements taken during exams, such as weight or blood pressure.
  • Always consult your healthcare professional if you have questions about your results before taking any action.

Labs Measuring Your Kidney Health

  • Serum (Blood) Creatinine
    • Waste product from protein digestion and muscle breakdown.
    • Removed by kidneys; high levels indicate potential kidney disease.
    • Normal levels vary by age, sex, and body size.
  • Cystatin C
    • Protein produced by body cells, also removed by kidneys.
    • Alternative or additional measure to creatinine for kidney health.
    • Less common and more expensive test.
  • Estimated Glomerular Filtration Rate (eGFR)
    • Estimates how well kidneys remove waste from the blood.
    • Calculated using creatinine, age, and sex; or cystatin C.
    • Key for determining CKD stage; eGFR below 60 indicates kidney issues, below 15 indicates kidney failure.
  • Measured Glomerular Filtration Rate (mGFR)
    • Direct measure of kidney function.
    • More accurate but complex and lengthy process.
    • Used in specific situations needing precise kidney function measurement.
  • Blood Urea Nitrogen (BUN)
    • Waste product from protein breakdown.
    • Evaluated alongside creatinine and eGFR for kidney health.
    • Normal levels vary with age.
  • Urine Albumin-Creatinine Ratio (uACR)
    • Measures albumin and creatinine in urine.
    • Indicates how well kidneys filter albumin.
    • Normal level is less than 30 mg/g; higher levels can signal albuminuria.
  • Urine Protein-Creatinine Ratio (uPCR)
    • Measures all proteins in urine, not just albumin.
    • Used for specific kidney diseases or pediatric testing.
    • Normal level is less than 150 mg/g; higher levels can signal proteinuria.

Measuring Your Balance of Important Minerals and Acidity

  • Potassium
    • Essential mineral for heart and muscle function.
    • Kidneys regulate blood potassium levels.
    • Goal level: 3.5 to 5.
  • Sodium
    • Balances body fluid, supports nerve and muscle function.
    • Kidneys help regulate fluid and sodium levels.
    • Excessive sodium can lead to high blood pressure and edema.
    • Limit intake to less than 2300 mg/day.
  • Serum (Blood) Bicarbonate/Carbon Dioxide (CO2)
    • Maintains blood acidity balance.
    • Low levels can indicate metabolic acidosis.
    • Goal bicarbonate/CO2 level: above 22 mEq/L.

You can always visit Understanding Your Lab Values or Blood and Urine Tests to learn even more.